1 - hyperprolactinemia mcqs

Question 1
Which of these pharmacologic agents does not induce hyperprolactinemia?
Neuroleptics
Antidepressants
Dopamine agonist------------
Metaclopramide

Question 2
Which of these disorders does not increase the risk of hyperprolactinemia?
Hyperthyroidism------------
Hypothyroidism
Chronic renal failure
Liver cirrhosis

Question 3
Which of these symptoms is rarely encountered in men with hyperprolactinemia?
Decreased libido
Erectile dysfunction
Oligospermia
Galactorrhoea-----------------

Question 4
Which of these symptoms are not seen in females with hyperprolactinemia?
Infertility
Galactorrhoea
Menstrual irregularities
Hirsuitism----------------

Question 5
Prolactin level should be measured in the:
Morning-------------
Night
After meal
Anytime

Question 6
Macroprolactinemia refers to:
A large pituitary tumor >10mm in diameter
A polymeric form of prolactin in which several prolactin molecules form a polymer------------------------
Macroprolactinoma
Prolactin level >500 µg/l

Question 7
Which neurotransmitter functions as a physiologic inhibitor of prolactin?
Dopamine-----------------
Adrenaline
Serotonin
Acetylcholine

Question 8
Which of these statements is not true with regard to pregnancy and prolactin secreting pituitary tumor?
There is risk of expansion of pituitary tumor during pregnancy
Pregnancy should be terminated--------------------
In case of microprolactinoma, medical therapy should be stopped as soon as pregnancy is confirmed
Periodic checking of prolactin is of no benefit

Question 9
Asymptomatic hyperprolactinemia requires:
Regular measurement of prolactin levels------------------
Dopamine agonist therapy
Surgery
None of the above

Question 10
Dose of cabergoline for prevention of lactation is:
Single dose of 1.0mg given as soon as possible-----------------
Single dose of 2.0mg given as soon as possible
1.0 mg given once in the morning and once in the evening
2.0 mg given once in the morning and once in the evening

Question 11
Which of these statements is true with regard to bromocriptine?
It is a dopamine antagonist
Effect of bromocriptine on plasma prolactin is short-lived, lasting for 8-12 hours--------------
Half-life of bromocriptine is 36 hours
Bromocriptine appears to be teratogenic

Question 12
If a patient with only mildly elevated serum prolactin level has a pituitary macroadenoma, the diagnosis is more likely to be:
Non-prolactin secreting pituitary adenoma---------------
Prolactin secreting pituitary adenoma
Any of the above
None of the above

Question 13
Dosage of cabergoline for management of hyperprolactinemia is:
0.5-1.0 mg once daily
0.5-1.0 mg once daily
0.5-1.0 mg twice weekly------------------
0.5-1.0 mg on alternate days

Question 14
Which of these is not an indication for surgery for prolactin secreting pituitary tumor?
Women who have a microadenoma, desire pregnancy, and cannot tolerate medical therapy
Patientrs who do not wish to take medical therapy for long-term
Patients who show progression after an initial response to medical therapy
First line of treatment for macroprolactinemia------------------

Question 15
Long term effects of hyperprolactinemia are:
Osteoporosis
Ischemic heart disease
None of the above
Both of above-------------